日日干日日摸-日日干天天操-日日干天天草-日日干天天插-精品一区二区三区在线观看-精品一区二区三区在线观看l

熱門搜索: 硫酸角質素(KS)ELISA試劑盒(種屬:魚) 白介素6(IL6)ELISA試劑盒(種屬:魚) 魚白介素10(IL10)ELISA試劑盒發貨及時 斑馬魚白介素12BELISA試劑盒發貨及時 兔載脂蛋白B(apo-B)ELISA試劑盒發貨及時 兔孕酮(PROG)ELISA試劑盒發貨及時 兔羥脯氨酸(Hyp)ELISA試劑盒發貨及時 兔抗酒石酸酸性磷酸酶ELISA試劑盒發貨及時 兔晶體蛋白α(Cryα)ELISA試劑盒發貨及時 兔結締組織生長因子ELISA試劑盒發貨及時 兔基質金屬蛋白酶9ELISA試劑盒發貨及時 兔肺表面活性物質相ELISA試劑盒發貨及時 CD206分子ELISA試劑盒(種屬:小鼠) CC趨化因子受體6ELISA試劑盒(種屬:小鼠) 阻抑素(PHB)ELISA試劑盒(種屬:大鼠) 中性內肽酶;腦啡ELISA試劑盒(種屬:大鼠)

技術文章/ Technical Articles

您的位置:首頁  /  技術文章  /  人不對稱二甲基精氨酸(ADMA)ELISA試劑盒 “仁捷生物”產品文獻

人不對稱二甲基精氨酸(ADMA)ELISA試劑盒 “仁捷生物”產品文獻

更新時間:2019-08-27      瀏覽次數:1596

“仁捷生物”產品文獻:Clinical Value of Asymmetrical Dimethylarginine Detection in Patients with Connective Tissue Disease-Associated Pulmonary Arterial Hypertension

-----------------------------------------------------------------------------------------------------------------------

 

Juan Liu , Qiang Fu, Lili Jiang, and Youlian Wang

Department of Rheumatology, Jiangxi Provincial People’s Hospital, Nanchang 330006, China

Correspondence should be addressed to Youlian Wang; 

Received 4 April 2019; Revised 29 May 2019; Accepted 27 July 2019; Published 14 August 2019

Guest Editor: Yan Yang

Copyright © 2019 Juan Liu et al.-is is an open access article distributed under the Creative Commons Attribution License, which

permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Objective. To evaluate the clinical value of serum asymmetrical dimethylarginine (ADMA) in patients with connective tissue

disease- (CTD-) associated pulmonary arterial hypertension (PAH). Methods. 88 patients with CTD were recruited between

December 2017 and August 2018 in Jiangxi Provincial People’s Hospital. Patients were further divided into two groups: CTD

without PAH (n = 45 cases) and CTD-with PAH (n = 43 cases), according to the pulmonary systolic blood pressure measured by

echocardiography. 40 healthy controls were also included (n =40 cases). -e clinical data, including laboratory examinations,

echocardiographic measurements, pulmonary function, and serum ADMA levels determined by enzyme-linked immunosorbent

assay, (ELISA) were collected. -e correlation between ADMA levels and the occurrence of PAH, pulmonary function, and other

laboratory indexes in CTD patients were analyzed. Statistical analyses were performed by SPSS (version 23); P < 0.05 was

considered statistically signifificant. Results. -e serum levels of ADMA in the CTD-PAH group were signifificantly higher than

those of the CTD-without PAH group and healthy control group (P < 0.05); the serum ADMA levels were (0.706 ± 0.153 μmol/L),

(1.015 ± 0.122 μmol/L), and (0.661 ± 0.113 μmol/L), respectively. -ere was no signifificant difffference between the CTD-without

PAH group and healthy control group (P < 0.05). Correlation analysis showed that serum ADMA levels were positively correlated

with sPAP and NT-proBNP and negatively correlated with DLCO% (r =0.802, 0.475, 0.585, P < 0.001). M*riate analysis

indicated that elevated serum ADMA levels increased the risk for the appearance of PAH in CTD patients (OR =57.460,

P < 0.001). Using the receiver operating characteristic (ROC) curve analysis, at the cutoffff level of 0.810 μmol/L, ADMA showed

good diagnostic effiffifficacy as follows: sensitivity was 97.7%, specifificity was 75.6%, and the area under the curve (AUC) was 0.947

(P < 0.001). Conclusion. Increased ADMA levels are independently associated with the presence and severity of PAH in CTD

patients. -e levels of ADMA in the serum may contribute to be a noninvasive indicator for early diagnosis of CTD-with PAH patients.

 

Blood samples for measurement of serum ADMA concentrations were naturally coagulated at room temperature for 20 minutes and centrifuged for about 20 minutes (3000 rpm), and the supernatants were stored in 1 mL aliquots at −80°C until further use. Concentration of ADMA was measured in serum samples by using an enzyme immunoassay ELISA kit provided by Shanghai Renjie Biotechnology Co., Ltd. The whole detection process was completed in strict accordance with the operating instructions. The absorbance (OD) was measured at 450 nm by using a Microplate reader, and each sample was duplicated.

 

ELISA試劑盒:人不對稱二甲基精氨酸(ADMA)ELISA試劑盒 

 

產品貨號:RJ11983

微信掃一掃

郵箱:2450868877@qq.com

傳真:86-區號-傳真號碼

地址:上海市楊浦區鐵嶺路32號1519-10室

Copyright © 2025 上海仁捷生物科技有限公司版權所有   備案號:滬ICP備16052159號-1   總訪問量:269137   技術支持:化工儀器網

TEL:17302193538

掃碼加微信
主站蜘蛛池模板: 新97人人模人人爽人人喊| 久久精品国产一区二区三区不卡| 日本女同按摩| 草β好视频| 日韩精品视频在线观看免费| 国产三级精品三级在线专区1| 亚洲人成电影院在线观看| 人妖视频在线观看专区| 国产精品久久久久影院| 麻豆女神吴梦梦| 李采潭一级毛片高清中文字幕| 水蜜桃视频在线免费观看| 波多野结衣和黑人| 老汉扛起娇妻玉腿进入h文| aaaa欧美高清免费| 黄色三级电影免费观看| 美女露内裤扒开腿让男生桶| 亚洲欧美一区二区三区| 夜夜操夜夜爱| 男生吃女生的jiojio| 成年女人免费播放影院| 嘟嘟嘟www在线观看免费高清 | 亚洲日韩中文字幕天堂不卡 | 日本三人交xxx69视频| 再深一点灬舒服灬太大了| 一区二区三区高清视频在线观看| 国产卡一卡二卡3卡4乱码| 天天色影网| 国产乱码精品一区二区三区四川人 | 奶特别大的三级日本电影| 一本大道一卡2卡三卡4卡麻豆| 欧美3p大片在线观看完整版 | 日韩欧美卡一卡二卡新区| 新梅瓶1一5集在线观看| 日韩aaa电影| 啊轻点灬大ji巴太粗小说太男| 正在播放久久| 午夜阳光电影在线观看| 黑人插入| 日本三级免费看| 欧美日韩成人在线观看|